ANTONIS ANTONIOU, PHD University of Cambridge, Co-Chair, Session 4

Professor Antoniou currently leads a research team within the Department of Public Health and Primary Care and he is the Academic Course Director for the MPhil in Epidemiology.

Professor Antoniou’s main research is the development and application of statistical modelling techniques for addressing clinical questions, and the development of cancer risk prediction tools which are used in clinical practice for cancer risk-stratification and prevention. He is the principal developer of the risk prediction algorithm “BOADICEA” for breast and ovarian cancer. He has developed novel statistical techniques for modelling disease susceptibility and has applied these methods for the accurate risk characterization of rare mutations in BRCA1, BRCA2, PALB2, and other cancer susceptibility genes. He established the data coordinating center of the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA), which aims to identify and characterize modifiers of cancer risk for BRCA1/2 mutation carriers, and has led the analytical efforts of the consortium since its inception.